PORTUGAL - The group of João Sanches from the Instituto Superior Técnico at the University of Lisbon, in collaboration with the group of Raquel Seruca from I3S/IPATIMUP in Porto, has developed a new, simple and effective assay to study the impact of cancer-related molecules in intercellular organization.
Intercellular adhesion is crucial to maintaining normal tissue architecture and E-cadherin is vital to assure that neighboring cells cluster to each other, establishing a correct epithelium. When E-cadherin does not function properly, cells become loose and the tissue becomes disorganized, which is a typical property of cancer.
This knowledge allowed the researchers to develop a new bioimaging strategy, based on the study of cell meshes organization, in order to infer the pathogenic value of E-cadherin mutations associated with cancer.
Madison, WI – May, 2015 – Papa Murphy’s of Dane County has announced that it will hold a fundraiser to benefit No Stomach For Cancer and its quest to support research and unite the caring power of people worldwide affected by stomach cancer. During the month of May, participating Papa Murphy’s locations in the Madison area will donate 10% of Wednesday sales to No Stomach For Cancer for every pizza purchased. This is the first year Papa Murphy’s has held the fundraiser and hopes to collect nearly $10,000 to benefit No Stomach For Cancer.
“Even if it’s only one person that benefits from this we’ll consider it a success,” said Mark Venditto, owner of the Papa Murphy’s in Fitchburg, Middleton, Madison, Waunakee, Oregon, and Verona stores. “I believe it’s our duty as a business in this community to help those in need of a helping hand. No Stomach For Cancer is the leader in raising gastric cancer
awareness and research; my employees and I are looking forward to this.”
“I cannot tell you how much our organization appreciates the generosity of Mr. Venditto,” said Jon Florin, Executive Director of No Stomach For Cancer based in Madison, WI. “His willingness to help us raise awareness and funds will go a long way to supporting the gastric cancer community and advancing research.”
Stomach cancer is the third leading cause of cancer death worldwide. Typically diagnosed at late stage, the 5 year survival rate for stage IV stomach cancer patients is only 4%, overall rate is about 26%. Almost one million new cases of stomach cancer were estimated to have occurred in 2012, making it the fifth most common malignancy in the world, with more
than 723,000 deaths annually.
About No Stomach For Cancer
No Stomach For Cancer, Inc. is a 501(c)(3) nonprofit organization whose mission is to support research and unite the caring power of people worldwide affected by stomach cancer. Serving families across the globe, NSFC advances awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provides a support network for affected families, and supports research for screening, early detection, treatment, and prevention of stomach cancer. Headquartered in Wisconsin and serving families across the globe, No Stomach For Cancer is a worldwide thought leader in stomach cancer awareness and education. For more information, please visit www.nostomachforcancer.org
About Papa Murphy’s
Papa Murphy's Holdings, Inc. (Nasdaq: FRSH) is a franchisor and operator of the largest Take 'N' Bake pizza chain in the United States, selling fresh, hand-crafted pizzas ready for customers to bake at home. The company was founded in 1981 and currently operates over 1,400 franchised and corporate-owned fresh pizza stores in 38 States, Canada and United
Arab Emirates. Papa Murphy's core purpose is to bring all families together through food people love with a goal to create fun, convenient and fulfilling family dinners. In addition to scratch-made pizzas, the company offers a growing menu of grab 'n' go items, including salads, sides and desserts. For more information, visit www.papamurphys.com. Find Papa
Murphy’s on Facebook at www.facebook.com/papamurphyspizza.
Beth Lambert Participates in Georgetown Event to Discuss Research, Awareness and Ongoing Importance of Educating At-Risk Patients
WASHINGTON, D.C. (November 17, 2014) – No Stomach For Cancer Board Member Beth Lambert today participated in a national forum hosted here by the Otto J. Ruesch Center for The Cure of Gastrointestinal Cancers at Georgetown. Speaking alongside other patient advocates, including Michael Sapienza of the Chris4Life Colon Cancer Foundation, Elizabeth Hoffler of the Prevent Cancer Foundation and Sharon Brigner of PhRMA, the conversation covered a range of topics, including the importance of empowering and educating patients about the preventive measures that can be taken to combat GI cancers, as well as the need to drive effective communication among stakeholders in the health care community and beyond.
“Today’s event is critical to elevating the conversation around GI cancers,” said Lambert. “This year alone, 22,000 people will be diagnosed with stomach cancer, many of whom could have benefited from greater awareness and education. Events like this help raise awareness about GI cancer broadly, as well as provide hope for the future of treatment options for patients.”
The forum also featured other notable health care leaders, including Dr. John Marshall, Director of the Ruesch Center, Dr. Allen Melemed, Distinguished Medical Fellow, Oncology, at Eli Lilly & Company, John Castellani, President and CEO of PhRMA, and Dr. Jeff Allen, Executive Director of Friends of Cancer Research. Congressional staff members Wade Ackerman of the United States Senate Committee on Health, Education, Labor & Pensions and Paul Edattel of the Committee on Energy & Commerce, United States House of Representatives also participated in the event, outlining the public policy landscape needed to advance GI cancer care research now and in the future.
“Unlike many other cancers — all of which deserve the highest degree of attention and engagement — stomach cancer is in need of greater resources, research andawareness. Our goal is to make all three happen.”
Founded in 2009, No Stomach For Cancer, Inc. is a 501(c)(3) nonprofit organization dedicated to raising awareness about stomach cancer. The organization’s mission is to support research and unite the caring power of people worldwide affected by stomach cancer. Headquartered in Wisconsin and serving families across the globe, No Stomach For Cancer is a worldwide leader in raising awareness and advancing education. For more information, please visit www.nostomachforcancer.org.
Featuring Leading Researcher Dr. Parry Guilford
[Madison, WI] -‐ No Stomach For Cancer is pleased to announce their “Spotlight on Gastric Cancer” event on Thursday, April 23 from 1:30-‐7:30 at the Temple University Center City Campus, 1515 Market Street in Room 222. The Keynote speaker will be Professor Parry Guilford, PhD, a principal Investigator in the Cancer Genetics Laboratory, University of Otago, Dunedin, New Zealand. Dr. Guilford is responsible for the discovery of the CDH1 gene mutation which has been identified in many families affected by Hereditary Diffuse Gastric Cancer (HDGC). Stomach cancers are the fifth most common cancer types worldwide, and the third leading causes of cancer death in the world.
HDGC is a rare form of stomach cancer that affects families that typically see several members diagnosed at early ages. Stomach cancer is very difficult to detect and is often not discovered until it is in an advanced stage. Because of this, carriers of the CDH1 gene mutation are advised to undergo prophylactic gastrectomy (complete removal of the stomach), much like BRCA gene carriers are advised to have mastectomy. Female carriers of CDH1 are also at increased risk of developing lobular breast cancer, so mastectomy is sometimes recommended for them as well.
Dr. Guilford’s presentation will cover the history of his HDGC research with families of New Zealand’s Maori tribe and discovery of the gene mutation, what is known about how the cancer starts and spreads, current guidelines for HDGC families plus updates on research that could involve new drug therapies, rather than surgical intervention.
In addition, the “Spotlight on Gastric Cancer” event will also feature a few HDGC families sharing their stories and a Q & A and roundtable discussion with Dr. Parry Guilford.
This event is being sponsored by Lilly Oncology and is free and open to anyone, however attendees must pre-‐register at www.nostomachforcancer.org as there is limited space. You can register for the event at this link…Spotlight on Gastric Cancer
Founded in 2009, No Stomach For Cancer is a 501(c)(3) nonprofit organization dedicated to facilitating research and promoting awareness about stomach cancer. The organization’s mission is to support research and unite the caring power of people worldwide affected by stomach cancer. Headquartered in Wisconsin and serving families across the globe, No Stomach For Cancer is a worldwide thought leader in stomach cancer awareness and education. For more information, please visit www.nostomachforcancer.org
Devens, MA – No Stomach For Cancer, a nonprofit organization dedicated to supporting research and uniting people worldwide affected by stomach cancer, is pleased to present a free Spotlight on Gastric Cancer program Saturday August 9, 2014 from 1pm-4pm at Devens Common Center in Fort Devens, MA. This educational event will review current perspectives and treatments for people living with Gastric Cancer, people living with Hereditary Diffuse Gastric Cancer (HDGC), their families, friends, and health care professionals. Presentations by renowned healthcare professionals will cover new treatments, latest clinical trials, genetic testing, targeted treatments, nutrition, the latest
research, and more.
“This gathering is much more than an educational panel,” said Beth Lambert, No Stomach For Cancer Board Chair. “It is an opportunity to connect with others who know the heartache that stomach cancer can cause, who have travelled the same journey as others affected by this terrible disease, and who want to hear from those who are in the trenches, those trying to eliminate this disease.”
Stomach cancer is the second leading cause of cancer death worldwide, with one million new cases diagnosed each year and more than 800,000 deaths annually. Stomach cancer currently receives the least amount of federal funding per cancer death in the United States. No Stomach For Cancer’s key priorities are to advance awareness and education about stomach cancer. This educational event will feature a panel of experts from numerous renowned medical centers, including Dana Farber/Harvard Cancer Center, UMass Medical Center, and Massachusetts General Hospital. No Stomach For Cancer recently awarded $100,000 for stomach cancer research. Hector Li Chang, who is on one research team that was awarded one of No Stomach For Cancer’s $50,000 grants, will moderate the event.
Spotlight on Gastric Cancer is a free event and open to all. No Stomach For Cancer requests that attendees RSVP by registering at www.nostomachforcancer.org/support-us/events. There will be a reception immediately following the Spotlight program.
About No Stomach For Cancer: Founded in 2009, No Stomach For Cancer, Inc. is a 501(c)(3) nonprofit organization dedicated to raising awareness about stomach cancer. The organization’s mission is to support research and unite the caring power of people worldwide affected by stomach cancer. Headquartered in Wisconsin and serving families across the globe, No Stomach For Cancer is a worldwide leader in raising awareness and advancing education. For more information, please visit www.nostomachforcancer.org.